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Lipid nanoparticles (LNPs) have been developed as a novel method for drug delivery. They are composed of a hydrophobic core surrounded by a lipid bilayer. LNPs offer many advantages over traditional delivery systems such as better stability and biodistribution. However, their chemical composition and physical properties can vary greatly depending on their method of production and formulation conditions. Lipid nanoparticles are an attractive delivery platform for therapeutics and vaccines due to their ability to protect drugs from degradation, target specific cell types, and minimize side effects. Characterization of LNPs is essential for understanding how they interact with cells and tissues, as well as for optimizing their formulation and manufacturing. With improved methods for LNP characterization, it may be possible to unlock the full potential of these particles for therapeutic and vaccine delivery.
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