| 1 |
Author(s):
Ms. Yogita R. Shirsath, Ms. Shaikh Sana Tahreem.
Page No : 1-3
|
REVIEW OF COMPUTER BASED SIMULATIONS IN PHARMACY EDUCATION
Abstract
Simulation in pharmacy education is the use of technology to create a realistic environment for educational purposes. This article reviews some of the most popular types of computer-based simulations, their advantages, and disadvantages, as well as methods for evaluating their effectiveness. It also looks at current trends in computer-based simulation and discuss ways in which such tools can be further improved. Computer-based simulations are a valuable tool for pharmacy education, allowing students to learn and practice the necessary skills in a safe environment. Some simulations allow students to practice pharmacokinetic calculations, while others focus on patient counseling or medication dispensing. They can also be used as an assessment tool to evaluate student's performance on specific tasks.
| 2 |
Author(s):
Dr. Prashant M. Tayade, Mr. Abhay Shripad Joshi.
Page No : 4-6
|
REVIEW ON PHARMACOVIGILANCE PRACTICES IN INDIA
Abstract
In India, pharmacovigilance practices have been
gradually evolving over the past decade in order
to better monitor drug safety metrics. The
traditional system of spontaneously reporting
adverse drug reactions (ADRs) to regulatory
authorities is no longer feasible, given the large
number of drugs and patients in India. There is
still a need for better coordination between
different stakeholders, and for more resources to
be allocated to such activities. This article looks
at some of the most recent developments in this
area, as well as their implications for patient
outcomes. The Pharmacovigilance Programme
of India (PvPI) was established in 2010 and is
managed by the Central Drug Standard Control
Organization (CDSCO). The PvPI monitors the
safety of medicines that are marketed in India,
with the aim of protecting patients from adverse
effects. It collects data on adverse events
through a reporting system accessible to both
health care professionals and members of the
public. The National Pharmacovigilance
Monitoring Centre (NADRMC) in India
monitors adverse drug reactions (ADRs) from
all over the country. The centre collects data
from various sources such as hospitals, clinics,
voluntary reporting by patients/caregivers and
health care professionals. This will help reduce
healthcare costs as well as protect patient safety
by minimizing risk of harm associated with
inappropriate use of drugs.
| 3 |
Author(s):
Dr. Yuvraj R. Girbane, Dr. Gajanan A. Vaishnav.
Page No : 7-10
|
REVIEW ON QUALITY BY DESIGN IN MICROWAVE ORGANIC SYNTHESIS
Abstract
The synthesis of organic molecules using
microwaves offers a range of advantages over
traditional methods, such as shorter reaction
times and higher yields. Quality by design
(QbD) is a systematic approach to the
optimization of synthetic routes and procedures
that seeks to ensure the quality of the final
product. QbD can lead to significant
improvements in product quality, process
understanding and productivity. The microwave
organic synthesis is a relatively new field, but
there are still many challenges associated with
quality by design. One of the main challenges is
to ensure that the desired product is obtained in
a reproducible manner. Another is to optimize
the reaction conditions to minimize sideproducts and maximize yield. This can be a
time-consuming and difficult process,
especially if the reaction is not well understood.
Quality by Design (QbD) is a systematic
approach to pharmaceutical development that
focuses on designing and controlling the
process. QbD can be applied to microwaveinduced organic synthesis by first identifying
the critical quality attributes (CQAs) of the
product, such as purity, yield, and stability.
Next, the critical process parameters (CPPs) are
identified and controlled through design of
experiments (DOE) and process analytical
technology (PAT) tools. Finally, process
controls and monitoring systems are
implemented to ensure that the process remains
in a state of control and consistently produces
the desired product quality.
| 4 |
Author(s):
Dr. S. G. Vaishnav, Dr. G. A. Vaishnav.
Page No : 11-13
|
REVIEW ON MANUFACTURING DEFECTS IN PHARMACEUTICAL TABLET DOSAGE FORM
Abstract
A review of manufacturing defects in pharmaceutical tablet dosage form was conducted to provide insight into the causes and prevention of these defects. Poor raw material quality, incorrect process parameters, inadequate cleaning/sanitation, and operator error are amongst the most common factors leading to defects. To reduce the risk of defective tablets, manufacturers should ensure that their raw materials meet quality standards, their processes are correctly controlled, operators receive proper training, sanitation is adequately monitored, and an effective quality management system is implemented. With these measures in place, manufacturers can help improve product quality while ensuring public safety.
| 5 |
Author(s):
Ms. Suwarna H. Kale, Abhay Shripad Joshi.
Page No : 14-16
|
AN OVERVIEW OF PHARMACEUTICAL SELF NANO EMULSIFYING DRUG DELIVERY SYSTEMS
Abstract
Self-emulsifying drug delivery systems
(SNEDDS) are transforming the pharmaceutical
industry, allowing drug delivery with greater
accuracy and efficacy than ever before.
SNEDDS are a type of drug delivery system that
uses nanoparticles to self-emulsifying drugs.
This means that the drugs are encapsulated
within nanoparticles, which can then be taken up
by cells and transported through the body. Read
on to learn more about SNED DS and how they
could revolutionize the way we administer
medication. Nano self-emulsifying drug
delivery systems (SEDDS) offer many potential
advantages over traditional drug delivery
methods, but there are also some disadvantages
to consider. One of the biggest disadvantages is
the potential for nano SEDDS to increase the
toxicity of drugs. These nanoparticles can
interact with cells and cellular components in
unexpected ways, potentially leading to
increased toxicity.
