Author(s) :

Ajay Jagannath Malode , Prashant Appasaheb Rode.

Volume/Issue :

Abstract :

A mouth dissolving tablet is a solid dosage form containing an active ingredient that dissolves within one minute in the oral cavity. Convenience of administration and improved patient compliance are important in the design of oral drug delivery systems, and oral drug delivery systems remain the preferred route of drug delivery despite various drawbacks. Such problems can be solved by prescribing “Mouth dissolving tablets” (MDT) that disintegrate or rapidly dissolve in the mouth without water within seconds due to the action of super-disintegrants, or by changing the pore structure of the oral cavity. can be solved in new drug delivery systems by maximizing pharmaceutical formulation. These dosage forms are placed in the mouth and dispersed or dissolved in saliva. There is no need for water during administration as the drug is released immediately upon contact with saliva. The purpose of this article is to review technological developments and advances in superdisintegrants in the formulation, manufacturing and evaluation of these tablets. This article also describes a new evaluation method for these orally disintegrating tablets. Various modifications in conventional evaluation and the use of specialized equipment have proven essential to testing these dosage forms. This review describes formulation techniques and different techniques.

No. of Downloads :

26