Author(s) :

Mrs. Dipali M. Kulkarni, Ms. Renuka B. Dhakne.

Volume/Issue :

Abstract :

The advancement of process analytical technologies (PAT) has revolutionized the pharmaceutical industry by providing faster, more accurate and cost-effective methods for analyzing drug quality. One particular application that has greatly benefited from PAT is tablet granulation processes, which are used to create tablets with uniform size and shape. Online PAT refers to the real-time monitoring of process parameters and quality attributes during granulation. It helps to optimize the process by reducing variability and improving product quality. The use of process analytical technologies (PAT) in the tablet granulation process can help to optimize and control the process, ensuring consistent quality of the final product. There are some drawbacks to using PAT, such as the need for specialized knowledge and skills and high initial investment costs. With further advances in this field, it is expected that PAT will become increasingly utilized by pharmaceutical companies worldwide.

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