| 1 |
Author(s):
Dr. Gajanan A. Vaishnav, Dr. S. G. Vaishnav.
Page No : 1-2
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AN IMPROVED PROTOCOL FOR RAT BRAIN SLICE PREPARATION: A REVIEW
Abstract
Brain slices are thin pieces of brain tissue that are used to study the central nervous system. They are commonly prepared from mice, rats, or guinea pigs and offer several advantages over in vivo methods, including precise control over experimental conditions, the ability to examine metabolic parameters and electrophysiological properties without the influence of anaesthetics or other substances, and improved stability for electrophysiological recordings. Brain slices can be used to study a variety of brain regions and are used in research applications such as the study of neuronal membrane properties, synaptic activity, and simple circuit function. However, brain slices also have limitations, such as a lack of certain inputs and outputs present in the intact brain, damage to the slice caused by the slicing process, a limited lifespan, and the potential influence of ischemia resulting from decapitation. The protocol for preparing a rat brain slice includes using materials such as a rat brain, ice-cold cutting solution, a vibratome or slicing apparatus, microscope slides, a dissecting microscope, a scalpel or razor blade, forceps or tweezers, and cover slips
| 2 |
Author(s):
Mr. Kaustubh S. Pishorkar, Dr. Rohit B. Chavan.
Page No : 3-4
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IMPROVEMENTS IN PROCESSS FOR ISOLATION OF BETA AMYLASE FROM SWEET POTATO: A REVIEW
Abstract
The isolation of beta amylase was conducted with modified procedure. Beta-amylase is an enzyme that catalyzes the breakdown of starch into glucose. It can be isolated from a variety of sources, including sweet potatoes. The isolation process typically involves several steps, including Homogenization, precipitation, purification, concentration, and crystallization. Highest concentration was obtained using centrifugation method.
| 3 |
Author(s):
Ms. Renuka B. Dhakne, Ms. Reshma R. Patil.
Page No : 5-6
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A REVIEW ON ISOLATION OF PLANT PIGMENTS BY COLUMN CHROMATOGRAPHY
Abstract
Methods described in literature for isolation of plant pigments by column chromatography are reviewed. Column chromatography is an effective way to isolate plant pigments. This technique can help scientists identify the different constituents of a sample and provide insight into their metabolic pathways. Column chromatography is a powerful technique used to separate and identify plant pigments. It is a reliable and economical method for extraction of these natural compounds from plants. Plant pigments play important roles in the growth and development of plants. Plant pigments have immense potential for use in pharmaceuticals, cosmetics, and food products.
| 4 |
Author(s):
Mrs. Dipali M. Kulkarni, Ms. Priyanka A. Kawade.
Page No : 7-9
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A REVIEW ON POLYMER MEMBRANE PERMEATION CONTROLLED DRUG DELIVERY SYSTEMS
Abstract
Polymer membrane permeation-controlled drug delivery systems (DDS) are effective in delivering drugs with a slow and steady rate, which is beneficial for treatments of chronic diseases. These systems are especially useful for achieving therapeutic concentrations of drugs in the body within a short period of time. In this blog post, we will explore the various advantages and disadvantages of using polymer membrane permeation-based DDS for drug delivery. Polymer membrane drug delivery systems offer many advantages over traditional drug delivery methods. They can control the release of drugs over a sustained period, which helps to improve patient compliance and reduce the risk of side effects. The molecular weight of the drug also affects its permeability, with larger molecules having a lower permeability than smaller ones.
| 5 |
Author(s):
Mr. Abhay Shripad Joshi, Dr. Ashok S. Narute.
Page No : 10-13
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ROLE OF ARTIFICIAL INTELLIGENCE (AI) IN NEW DRUG DISCOVERY: AN OVERVIEW
Abstract
By accelerating and improving the drug discovery process, artificial intelligence (AI) has the potential to completely transform the area of pharmacology. Large data sets can be analysed using this technology, which can also be used to find novel therapeutic targets and compounds, forecast the effectiveness and toxicity of possible medications, and enhance the attributes of pharmacological molecules. AI can also help with the creation of tailored medicines and clinical trials. We address the existing and potential uses of AI in the field of pharmacology in this paper, focusing on how it might increase the speed and accuracy of the drug discovery process. Overall, the use of AI in pharmaceutical investigations has the potential to result in the creation of brand-new, better ways to treat a variety of illnesses.
